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In accordance with several other groups, we found 177Lu-DOTATATE PRRT dosimetry based only on 2-D scanning problematic due to inherent difficulties of delineating healthy organ uptake from tumours and physiological uptake as in the bowel [12, 28, 29].
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Furthermore, during import, datasets are scanned for problematic molecules or features of molecules like Pan Assay Interference Compounds (PAINS), which may disturb the assay setup or unspecifically bind to diverse proteins [26].
Although attempting to locate sulcal landmarks on an averaged MRI scan is problematic, the medial PFC activity observed in the present data does appear to be in the vicinity of the participants' average paracingulate sulcus location (most clearly illustrated in the right panel of Fig. 3c).
The complexity of the LC architecture and the need to measure minute focal changes to detect disease progression make low scanning resolution especially problematic.
The production of removable dentures from intraoral scans has been problematic.
The low specificity of the visual PET scan assessment is problematic, but this could be significantly increased by improvements in the spatial resolution of tomographs as well as by the use of appropriate training programmes for raters, and by the development of semiautomatic or automatic quantifications method or software.
While you're going about your daily life, your phone could be constantly scanning for hints of problematic behavioral changes, alerting your doctor when things veer off-course.
While you're going about your daily life, your phone could be constantly scanning for hints of problematic behavioural changes, alerting your doctor when things veer off-course.
However, precise digitization of the 3D morphological structure of a neuron acquired through various microscopy methods, such as 3D laser scanning microscopy, remains very problematic in practice.
Limitations included variation in handwriting in self-completed forms, which made electronic scanning of free text entries problematic.
Hand-held devices scan smartphones for content deemed problematic.
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CEO of Professional Science Editing for Scientists @ prosciediting.com