However, using a combinatorial peptide library scanning approach, we identified a CDH13-derived peptide activating the 7B5 T cell clone.
Even if this is the most convenient scanning approach and the data can be processed very easily after measurement, it leads to a large loss of data already during the scanning process.
Therefore, a conventional motif scanning approach using a single PWM for each TF has an intrinsic limitation in detecting all functional TFBSs.
To this end, we used a chromatin immunoprecipitation (ChIP) scanning approach [23] to systematically locate the GR binding regions in the vicinity of the human DUSP1 transcription start site (TSS).
Additional tests for recombination were conducted in RDP3, using a UPGMA-based pairwise scanning approach [ 63].
For these reasons, we adopted the distal end beam scanning approach.
We used two additive models and the haplotype phylogeny scanning approach of Templeton (Tree Scanning) to evaluate association between individual SNPs, all SNPs at a gene, and diplotypes, with log-transformed gene expression.
To identify the exact binding site of OCT1 on synbindin promoter, we developed a sequence scanning approach using the 3DTF method 25 based on the crystallographic data on the OCT1 protein DNA complex (pdb entry: 1O4X).
We adopted a high-resolution multi-slice pQCT scanning approach for quantification, which was found to give more accurate results than individual sections that were more susceptible to positional effects.
It is noted that the extra benefit of the distal end scanning approach is the ease in setting the desired focal position outside the plastic sheath, e.g., by adjusting the separation between the microreflector and the fiber-lens assembly.
The scanning approach could invite pranks — as the notification form already has.
