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Debbie McGibbon from Nepean Blue Mountains Local Health District for assistance with survey management, data scanning and validation.
The complete results of genome scanning and validation can be found in Table A3 and Table A4.
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Although the present results support the observation made by Duffin et al that the effect of rs1800925 is limited to PsA, 15 they contradict the findings reported by Nair et al. 11 That PsV GWAS contained a significant proportion of PsA cases in the primary scan and validation stages, where upon subgroup analysis there was significant association to both PsA and PsV.
The hybridization, scanning procedures and validation of microarrays has been described previously by our group [37].
The goals of AIDHS/SDS are to discover unique genetic markers associated with type 2 diabetes (T2D) and related metabolic and lipid traits by performing genome-wide association scans (GWAS) and validation studies.
Therefore, B-scans pertaining to the same C-scan were split across training and validation sets in the cross-validation while all B-scans comprising all C-scans from one patient were kept together and classified using all C-scans from other patients in the leave-one-patient-out procedure.
The XML Screamer integrates the scanning, parsing, validation and deserialization process in a single low level tool, making unnecessary creating and catching SAX events.
Sequence retrieval, BLAST scans, identification, validation and annotation of hits and all associated parsing of text files were carried out in batch mode with scripts written in Perl5 [87], using modules from the BioPerl library [88] and are available from the authors on request.
In addition, this is one of the first instances of highly significant, independent replication of data derived from a genome-wide association scan and provides important validation of this technique as a hypothesis-free method for the identification of complex disease genes.
Results of F-NaF PET/CT scanning were then communicated to the referring orthopedist and tabulated in detail for analysis and validation (Table 1).
The calibration and validation sets, and real samples spectra were collected with 32 scans from 850 1200 cm−1.
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