Sentence examples for scan linkages from inspiring English sources

A compendium of evidence for the genetic bases of obesity have been accrued from single-gene mutation studies, Mendelian inheritance patterns, transgenic and knockout murine models, animal and human quantitative trait loci (QTL), candidate-gene association studies, and genome scan linkages and have been incorporated into the Obesity Gene Map database [ 3].

Overall, genome scan linkage analyses showed peaks with higher LOD scores in Dielmo than in Ndiop.

It is interesting to note that although the heritability of the mean P. falciparum asymptomatic trophozoite density (me-tPFD) did not reach significance in Ndiop, genome scan linkage analysis revealed a LOD score of 2.08 (empirical p = 0.005) by VCM and LOD = 1.06 (nominal p = 0.014) by regression analysis in the region of the β-globin cluster on chromosome 11p (Figure 2).

For each QTL identified by the across-family LA scan, linkage-based within-family analyses were performed to identify the corresponding segregating families.

We have already genotyped 419 short tandem repeats (STRs) in this sample in the initial whole genome scan linkage studies [ 18, 19], and inferred the ancestry proportions in each individual.

Here, in what we believe is the first study of its kind in humans, we have revisited microsatellite genome scan linkage data for three infectious diseases in contrasting populations, to determine the extent to which genomewide heterozygosity is an important predictor of susceptibility to some diseases, particularly in populations where inbreeding is common.

We performed genome-scan linkage analysis of several malaria-related phenotypes both during clinical attacks and asymptomatic infection.

Nevertheless, the lack of genome-wide association studies or whole-genome-scan linkage studies in GCA makes necessary an independent replication study to confirm our results by using a population of a different genetic background.

To map the genes that modified the heart failure phenotype, progeny from the 2 reciprocal backcrosses were used in a genome-wide scan for linkage.

Initial localization to Chr. 9 was based on a genome-wide scan for linkage using Mit markers.

The only previous genomewide scan for linkage to longevity was conducted in part by a member of our group (LMK) and identified a region on chromosome 4q22-25 asignificantlylinkedked in 137 sibships of centenarians and nonagenarians [24].