The current version of ENISI incorporates Cellular Scale, Chemokine Scale and Tissue Scale.
"It can fabricate stable, human-scale tissue of any shape.
Additionally, we discuss driving mechanisms for self- and guided assembly to create micro-to-macro scale tissue structures.
A combination of approaches such as gene therapy, stem cell transplantation, macro- and micro-scale tissue engineering, functionalized biomaterials, and the reprogramming of cell and tissue types is utilized.
Similarities between embryogenesis and regeneration, particularly with regards to pattern formation and large-scale tissue movements, suggest similarly important roles for physical forces during regeneration.
In this work, our team reports on the development of piezoresistive microcantilevers (PMCs) to investigate their potential use in the accurate detection and characterization of benign and diseased breast tissues by performing indentations on the micro-scale tissue specimens.
The three-dimensional geometry of the gravid uterus has been reconstructed from segmented in vivo magnetic resonance imaging as well as ex vivo diffusion tensor magnetic resonance imaging to resolve fine scale tissue architecture.
Quantifying mechanically-induced changes in the tricuspid valve extracellular matrix (ECM) structural components, e.g. collagen fiber spread and distribution, is important as it determines the overall macro-scale tissue responses and subsequently its function/malfunction in physiological/pathophysiological states.
It is our belief that with efforts combined from multiple disciplinary participants, a novel bioreactor system that is capable of fast, large scale tissue culture would come about in near future.
To address this need, we produced a functional three-dimensional model of HGPS that replicates an arteriole-scale tissue engineered blood vessel (TEBV) using induced pluripotent stem cell (iPSC -derived SMCs from an HGPS patiPSC -derived
