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The extrapolation of dose across species is typically performed by scaling in relation to body weight or through the use of physiologically based pharmacokinetic (PBPK) models.
Turner DA (2016) Enhanced Functional Outcome from Traumatic Brain Injury with Brain-Machine Interface Neuromodulation: Neuroprosthetic Scaling in Relation to Injury Severity.
Turner, DA. "Enhanced functional outcome from traumatic brain injury with brain-machine interface neuromodulation neuroprosthetic scaling in relation to injury severity". In Translational Research in Traumatic Brain Injury, 365-378.
This section analyzes that characteristic scaling in relation to the Hill equation and biological input-output patterns.
That scaling of objects in your office with the length of the ruler means that those objects have a natural linear scaling in relation to your ruler.
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Energy consumption can also be scaled in relation to throughput requirements and available bandwidth by modifying the coding rate and modulation scheme [24].
These maps are known for more accurately portraying the world's land masses to scale in relation to each other than familiar standard maps, which still "rely on the work of mapmakers of the age when Europe dominated and exploited the world.
In other words, results provide no evidence that reaction time scaled in relation to target size [cf. 13], [41].
Blackbox labeled a startup as scaling prematurely in relation to its customer acquisition when it, for example, spent too much money on acquisition before truly refining its actual product or market fit — or, alternatively, overcompensating or missing product and market fit with too much of a focus on marketing and press spending.
Understanding spatial heterogeneity at a fine spatial scale in relation to heat and related mortality is central to target interventions towards vulnerable communities.
This default value has been chosen, as it proportionally scales waveforms in relation to torso diagrams that are approximately the size of an A4 piece of paper.
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