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All clinical sedation scales suffer from several weaknesses - they are highly subjective, and some of the commonly used scales, such as the Ramsay scale [62] suffer from significant inter-rater variability [63].
Regrettably however, these scales suffer from irrelevant content.
Existing nursing scales suffer from a number of limitations.
However, the currently available scales suffer from a number of important shortcomings such as time for administration, validity concerns, and item difficulty.
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However, as shown above, most scales suffered from ceiling effects; four participants who made positive comments for the outcome variable all scored 4 or 5/5 at baseline deteriorating by 1 or 2 points at follow up.
Also here, one may hastily conclude that patients scoring high on the stagnation scale suffer from body/mind obstruction owing to a repressing of emotions.
More specific data, for example on a local scale, suffer from the small-number problem, in that estimates for rare outcomes may be highly unstable.
High-throughput experimental approaches aiming to specifically determine the components of protein complexes on a proteome-wide scale suffer from high false positive and false negative rates (von Mering et al., 2002).
Indeed, we found that diabetic adults who hold the lowest position on the educational scale suffer 503 excess deaths per 10,000 person-years of follow-up than those with the highest position, a gap 73% higher than in the nondiabetic population.
Meanwhile, it may be scant comfort to the Greek people, forced to endure a collapse in GDP and a rise in unemployment on the scale suffered by the US at the time of the Great Depression, that their grief is perhaps just one strand in a "three-part crisis trilogy" of the 2008 crash, the eurozone meldown of 2011 and now the emerging markets.
Those physicians in the top half of the hostility scale suffered five to six times more heart attacks than those in the lower half.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com