Landscape may no longer be viewed as a segment of the geographical world real, perceived or imaginary but rather as a situated image or system at the interface of different scales of contact with an "observer".
We confirm that the contact frequency maps produced by TM3C exhibit features characteristic of existing genome architecture datasets, including the expected scaling of contact probabilities with genomic distance, megabase scale chromosomal compartments and sub-megabase scale topological domains.
We apply TM3C to two human cell lines and confirm that the DNA DNA contact matrices produced by TM3C exhibit features characteristic of existing genome architecture datasets, including the expected scaling of contact probabilities with genomic distance, enrichment of intrachromosomal contacts, megabase scale chromosomal compartments and sub-megabase scale topological domains.
The critical conditions for self collapse of scales and scale contact give analytically the maximum and minimum widths of scales, which are important to the scale design.
Most of these correlation coefficients are below 0.2 and the alpha coefficient of first contact (access) scale is below 0.7, which suggest further improvement of PCAT-T, especially in the scale of first contact (access).
This correlated well with the time scale of putative contact formation (Fig. 1E).
From the PCAT-T results among different healthcare settings, we found that township health centers achieved the highest score, especially on the scale of first contact (access), which means patients can receive health care without waiting for a long time (less than thirty minutes) and can receive the needed service more easily in township health centers.
The characteristic frequency f c, around which |T| (or reflectivity |R|) has a good sensitivity to the interface strength, is shown to be proportional to the strength and inversely proportional to the representative scale of real contacts.
We consider two different scenarios for the simulation of epidemic spread: in the first scenario, the latent period is set to 2 days and the average infectious period is 1 day, whereas in the second scenario we halve these intervals in order to better probe the interplay with the fast temporal scale of human contacts.
This method, called cascade multi-resolution (CMR), takes advantage of physical considerations regarding the scaling of the contact predictions by changing the surface resolution.
