Sentence examples for scalable expansion from inspiring English sources

Large numbers of human mesenchymal stromal cells (MSCs) used for a variety of applications in tissue engineering and cell therapy can be generated by scalable expansion in a bioreactor using microcarriers (MCs) systems.

Substantial progress has been achieved with respect to culture conditions that support the long-term and scalable expansion of hESCs/hiPSCs [1] [4], but current techniques still do not allow efficient, economized large-scale production.

Therefore, the commercial viability and clinical translation of MSC therapies, especially those using allogeneic off-the shelf strategies, are hindered by challenges of scalable expansion of these cells [ 8].

Moreover, the observation that one of the cell lines could be passaged up to 10 times in commercially available serum-free defined media on this PMEDSAH surface is a significant advancement in achieving scalable expansion of hESCs for biomedical applications.

One potential method of scalable expansion of MSCs involves the use of bioreactors for suspension culture and the use of 150 200 μm beaded microparticles, referred to as microcarriers, as cell adhesion supports.

We invested the time at the beginning to build what we hoped would be an easily replicable structure and a scalable model of expansion both for Deric and for the community groups.

The company has just two full-time staff right now, but founder Jeremy Yamaguchi says that since the platform is easily scalable, further geographic expansion will be on deck in the weeks ahead.

Hampering the faster implementation of the ambitious stem cell therapy technology, there is still the need of efficient, robust and scalable bioprocesses for cell expansion and/or differentiation in vitro.

Realizing the potential of human pluripotent stem cell (hPSC -based thPSC -basedires therapyelopment of defined scalable culturequiresms witheefficient expansion, developmenttiof andefinedtion protocolscalable

However, an effective and scalable polymeric substrate for hPSC expansion has yet to be found.

However, the scientific and clinical application of hNPCs requires the development of robust, defined, and scalable substrates for their long-term expansion and neuronal differentiation.