LINKS is a scalable, alignment-free scaffolder, which extracts spaced k-mers from reads as its pairing information source to order and orient sequence contigs into scaffolds.
Spectral alignment-based approaches are more efficient and scalable than alignment-based ones, and adapted to low error rates.
The 15 day plan provides a wannabe startup with market research, strategic alignment, scalable revenue model, instruction manual for project completion and a concept summary delivered as a "Biz in a Box".
This analysis is very fast and scalable, because no alignment with germline sequences is required.
The defining feature of CGR derived distance metrics, and the reason for betting on them as replacements for the less scalable dynamic programming alignment procedures, is that they rely solely on the coordinates of the two sequence units being compared.
SeqCentral offers highly-scalable genetic sequence alignment in the cloud.
Nevertheless, the Graemlin algorithm was the first algorithm capable of performing scalable, multiple network alignments [ 39].
As alignment-based methods may be computationally expensive and not scalable to huge datasets, alignment-free methods have been extensively investigated recently.
By avoiding mutual comparisons between the sequences considered for inclusion in the final MSA (candidate sequences), the alignment process becomes inherently scalable.
The Ntshembo intervention is novel, both in SA and globally, and could prove to be both scalable and sustainable due to its alignment with health service priorities in SA.
This analysis is based on a seed heuristic and is fast and scalable because in the first phase, no alignment is performed with germline database sequences.
