Sentence examples for sc defects from inspiring English sources

Thus, in this context, levels of nondisjunction are being used as a "readout" for meiotic SC defects.

The increase of claudin-1, a tight junction protein, suggests a compensatory mechanism to overcome SC defects.

We have modified our comment in the introduction to clarify that SC defects have been associated with specific cases, with figures relating to the overall incidence of these conditions.

These data, together with our time-course experiments, strongly suggest that the high-temperature SC defects in both the wild type and the pgl-1 mutant primarily reflect an impairment in assembly of the central region of the SC.

The similarity in pairing defect to the SC-defective mutants suggests that SC assembly fails in the pgl-1 (bn102 ) mutant at 25°.

Increased expression of cell cycle inhibitors may lead to HF-SC proliferation defects.

SC-RbKO mice exhibited an age-dependent testicular atrophy, impaired fertility, severe SC dysfunction, and spermatogenic defects.

Defects in SC function have been associated with a number of neuropathological and neuropsychiatric disorders including epilepsy (Ross and Coleman 2000), schizophrenia (Fuentes 2001) and autism spectrum disorder (ASD) (Kleinhans et al. 2011).

Collectively, these defects in SC differentiation lead to a substantial reduction in viability, which we suggest is caused by defective excretion, as animals become bloated with fluid and the tubules fail to respond to diuretic stimuli, producing only very low levels of secreted primary urine.

Taken together these data suggest that at least part of the defect in barrier formation in SCARKO mice may directly be caused by defective SC function.

Here, we report that CB-SC can correct functional defects of mouse CD4+CD62L+ Tregs, leading to reversal of overt diabetes in an autoimmune-caused diabetic NOD mouse model.