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However, we achieved satisfactory local control with acceptable toxicity by using CCRT because IMRT achieves excellent target coverage and dose conformity, as well as favorable survival and locoregional control rates with acceptable toxicities in patients.
These include the adoption of an Interfant-99-based induction given its satisfactory CR rate and acceptable toxicity profile, the necessity of an extended continuation to prevent late relapse and mandating enhanced aggressive supportive care measures to minimize risk of infection.
According to previous studies, the effectiveness of gemcitabine is demonstrated with satisfactory response rates and acceptable toxicities.
The safety profile was satisfactory without overlapping toxicities.
But the results were not so satisfactory because of toxicities.
Although not generally resulting in satisfactory clinical outcomes, toxicities and side effects can arise, further complicating the picture.
This treatment administration as well as the tolerance profile can be considered as satisfactory regarding the toxicities observed although a reduction of administration of gemcitabine was required in two-thirds of the patients.
However, given the enormous biological diversity and unique chemistry of gluten, and the absence of satisfactory assays for gluten toxicity, the structural basis for gluten toxicity in CD remains unclear [ 14].
The agreement between the experimental and calculated toxicities is satisfactory, as shown in Figure 32A.
This dosing interval could be extended to a maximum of 35 days in the event of persistent toxicity to allow satisfactory recovery from the previous cycle.
This combination may provide a satisfactory degree of efficacy with less toxicity than cisplatin-based regimens.
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