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He was executed before the advent of DNA technology, and forensic experts have previously been unable obtain anything that might allow them to build a satisfactory profile.
Although limited data are available on the optimal medical treatment of osteo-articular invasive aspergillosis, voriconazole, the only azole agent licensed for use in invasive aspergillosis, has the most satisfactory profile for osteo-articular aspergillosis, including efficacy, diffusion and bioavailability allowing oral use for prolonged treatment [ 5].
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These compounds showed antiparasitic IC50 values ranging from 4.02 to 0.03 μg/mL and satisfactory cytotoxicity profile.
Consequently, a number of structurally diverse compounds were successfully identified to exhibit satisfactory inhibition profile against mTOR with IC50 values at nanomolar level.
In addition, a number of the innovative antimetabolite-type molecules have been preselected that possess the optimum lipophilicity range significantly correlated with some in silico bioactivity descriptors relevant to the satisfactory pharmacokinetic profile in vivo.
We confirmed that a nonvolatile by-product AuFx was re-deposited on the surface, but controlling the amount of carbon fluoride provided a good etch rate with a satisfactory sidewall profile by reducing by-products.
In addition, high-dose intermittent oral folic acid given in this study allowed administration of pemetrexed at the dose and schedule explored with a highly satisfactory safety profile and with no apparent compromise in efficacy.
A satisfactory chromatographic profile for analysis of the reaction mixture of amide surfactant synthesis was obtained with ELSD detector (Figure 1C).
Nine primer pairs with a satisfactory amplification profile and high polymorphism were evaluated for their use in assessing genetic variability.
Bioprostheses do not require a lifelong anticoagulation as opposed to mechanical prostheses and offer a satisfactory haemodynamic profile.
Notably, this schedule has been recently proposed for systemic onset juvenile arthritis (SoJIA), so far with a satisfactory safety profile [ 21].
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