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As for toxicity/risk of citrate accumulation, Chadha et al. [93] showed, in a series of 5 patients undergoing continuous venovenous hemofiltration, satisfactory clearance of calcium-citrate complexes.
As for toxicity/risk of citrate accumulation, Chadha et al. [ 93] showed, in a series of 5 patients undergoing continuous venovenous hemofiltration, satisfactory clearance of calcium-citrate complexes.
Eight (20%) in the weekly and 5 (12%) in the 3-weekly groups required further surgery to achieve satisfactory clearance (p = 0.36).
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On logistic regression, ScvO2 < 70% at H6 was independently associated with day-28 mortality in the subgroup of patients with non satisfactory lactate clearance (OR = 2.32 (1.03, 5.23)) but not in patients with satisfactory lactate clearance (OR = 0.98 (0.21, 4.54)).
Since UCNPs share a similar matrix, is it possible to make UCNPs possessing satisfactory renal clearance?
The other study, in a supplement issue, showed no differences [ 37] - here also, the peritoneal dialysis regime was unlikely to be sufficient to obtain satisfactory solute clearance.
Among the 335 patients with lactate and ScvO2 measured at H0 and H6, 148 (44%) had a satisfactory lactate clearance (defined as at least a 10% decrease between H0 and H6 [ 25]) and 187 (56%) had not.
Interestingly, our results suggest that, rather than choosing one of these measurements, ScvO2 should be tested in combination with lactate monitoring because low ScvO2 may be present or persist even in the case of low lactate, or in the case of satisfactory lactate clearance (see Figure 3 and Additional file 6).
Since UCNPs share a similar matrix, is it possible to make UCNPs possessing satisfactory renal clearance? 5. Development and application of 800 nm excited Nd-Yb-Er/Tm tridopant UCNPs in biomedical photoreactions is encouraging to overcome the potential water heating effects in 980 nm.
It showed a beneficial pharmacokinetic profile in rats, having a high oral bioavailability of 75% and satisfactory values of clearance and volume of distribution.
Patients were required to have Eastern Cooperative Oncology Group performance status ⩽2, adequate bone marrow reserve (WBC count ⩾3.5 × 10 l−1, platelets ⩾100 × 10 l−1 and haemoglobin ⩾10 g dl−1) and satisfactory renal function (creatinine clearance ⩾60 ml min−1 measured by Cr EDTA or Cockcroft and Gault estimation).
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