The data in this paper demonstrate that bound metabolites of the hypoxia marker NITP can be detected in tumours following oral administration of an aqueous formulation of NITP, and suggest that oral administration could be a satisfactory administration route for clinical studies with NITP.
About one third of study patients with chronic pain had satisfactory analgesia with the administration of buprenorphine.
However, none of these drugs achieved a satisfactory result and the combined administration of antithrombotic agents may provide a multipronged approach to the treatment of severe sepsis.
Satisfactory implant stability was accomplished upon administration of MBB graft.
The custom-made administration system and neutron-activation/administration vial was tested as well and found satisfactory for the neutron activation and the administration of Ho-PLLA-MS.
In this regard, the IMDDS may provide a more satisfactory means of access than the systemic administration of drugs through the blood vessels or oral uptake.
Notably, immune responses to JE vaccines were satisfactory in all groups, implying that simultaneous administration of other vaccines should not be a major concern with respect to JEV immunity induced.
A satisfactory compromise for some patients is twice-daily administration of mixtures of intermediate-acting and short-acting insulin.
In the presence of drug hypersensitivity, it is sometimes necessary to re-institute administration of the implicated drug because no satisfactory alternatives are available.
However, it took several hours to obtain satisfactory contrast between the tumor and normal tissues after administration of the radiolabeled agent.
This treatment administration as well as the tolerance profile can be considered as satisfactory regarding the toxicities observed although a reduction of administration of gemcitabine was required in two-thirds of the patients.
