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The structure activity relationships (SARs) of the substituents on each position (R2, R3, R5 and R5′) were investigated.
To investigate the SARs of thieno[3,2-d]pyrimidine derivatives in more details, CoMFA (q2 = 0.436, r2 = 0.937) and CoMSIA (q2 = 0.706, r2 = 0.947) models on H460 cell line were established.
We describe the discovery and structure-activity relationships studies (SARs) of a series of novel biphenyl imidazole derivatives with excellent antifungal activities against Candida albicans and Cryptococcus neoformans.
Structure activity relationships (SARs) of (2-oxoindolin-3-ylidene)methylpyrrole have been comprehensively investigated in previous works [20 26].
The team helped identify sars, of course, and Dowell was one of the authors of the initial report characterizing the virus.
The structure-activity relationships (SARs) of these derivatives were discussed.
The structure activity relationships (SARs) of the derivatives were analyzed.
Structure activity relationships (SARs) of prepared compounds were discussed.
The SARs of tropinone derivatives provided potential compounds for further investigation on antitumor regents screening.
And the structure-activity relationships (SARs) of these novel compounds were also briefly discussed.
In the following, we describe how the descriptor rankings relate to the SARs of the ORNs in this study.
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