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The catheter was filled with Li-heparin (LEO Pharma, Longwick Road, Princes Risborough, Buckinghamshire, HP27 9RR, United Kingdom) until the start of blood sampling and between samplings to avoid clotting.
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We used representative slides of surgically resected CRC samples to avoid sampling error due to small sample size.
These skin flaps were also identified in the segmented micro-CT data, and later excluded from optical sampling to avoid sampling and modeling problems.
Two sampling holders were also changed during the sampling period to avoid overload (the holders are marked as " ∗ " in Table 2 and the data expressed as TWA concentration).The sampling with personal samplers was performed during the normal work period from 09 30 to 16:00 and typically lasted from 159 to 350 min.
First, the number of people surveyed varied by location and it was important to adjust for these sampling changes to avoid clusters that are driven by the number of people surveyed rather than the number of people who had infection.
Future studies should further evaluate the accuracy of these two sampling media in a random sampling sequence to avoid any potential bias.
Increasing sampling frequency and/or targeted high flow sampling are more efficient approaches to ensure sufficient sampling and to avoid poorly performing models, than increasing calibration period length.
In the above equation, the matrix U represents an up-sampling operator needed to avoid any aliasing of the modulated signal due to a lack of sampling resolution in a digital description of the originally analog problem.
As discussed above, our algorithm is fairly insensitive to sampling bias and we try to avoid sampling bias by down sampling that data to similar numbers of sequences from different geographic regions.
While the sampling scheme was designed to avoid the sampling of clones, clonal identification was still required as to not bias the data set toward over-represented lineages (Arnaud-Haond et al. 2007).
Considering the intense breeding of European dogs during the last few 100 years, giving severe breed-specific bottlenecks (Clutton-Brock, 1995), special care was taken to avoid sampling bias by sampling a single individual per breed, from different morphological types and from across Europe.
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