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Application such as particle sampling, concentration and analysis on superhydrophobic surfaces should be dedicated to environment control.
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The aim of the present study was to obtain, by microdialysis sampling, concentration--time profiles in a solid tumour (melanoma) of a model anti-cancer drug, carboplatin, and thereby to assess the scope of microdialysis for tumour pharmacokinetic studies in man.
Sample concentration providing 50% inhibition (IC50) was calculated by plotting the inhibition percentage against sample concentration.
Each sample concentration and a control was replicated three times.
Sample concentration providing 50% inhibition (IC50) was calculated from the graph plotting inhibition percentage against sample concentration.
The system was linear (R2>0.99) within the working sample concentration and sample volume ranges.
Conditions: sample volume 5.0 mL; sample concentration 0.5 μg mL−1; picric acid concentration 1 × 10−3 M.
The sample concentration providing 50% inhibition (IC50) under the assay condition was calculated from the graph of inhibition percentage against sample concentration.
There is a clear distinction between the signal intensity and the logarithm of the sample concentration.
The focal length is critical for the design of micro sample concentration devices.
After sample concentration the dispensing granule came into being from water extracts by freezing drying.
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