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In fact, when all samples with point mutations were grouped together, a significant association was found.
However, when samples with point mutations were grouped together, MLH1 expression was significantly decreased (p = 0.019; Figure 1D).
Samples with point mutations (BRAF, IDH1 and NRAS) show a decrease in MLH1 expression when compared to negative samples.
Quantification of mosaicism in samples with point mutations was carried out by Pyrosequencing on a PyroMark Q96 MD (Qiagen, Hilden, Germany) of control and patient samples prepared by PCR, with each assay performed on three independent reactions as previously described (14).
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Hourly BG measurements were most frequently obtained by fingerstick capillary sampling; however, venous and arterial sampling with point-of-care glucometer, blood gas analyzer and central laboratory measurement were also included, reflecting a real-world clinical context.
We conducted two DCAs: one using all point counts as the sampling units and another using transects as the sampling units (with point counts pooled within each).
The data used to derive the correlation included samples with bubble point viscosity from less than 0.1 14,000 cp.
Tsuda et al 13 found only two tumour samples with Ras point mutations from 30 patients with HCC.
We sampled birds with point counts and evaluated structural connectivity considering the presence of corridors and the degree of isolation.
Compact bone tissue samples are indicated with green points and trabecular tissue samples with red points.
Figure 4(a) shows the irregularly spaced samples with 32-point from the test signal.
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