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Using fluorescence imaging analysis and oxygraphy on human and rat skinned skeletal muscle samples, we show that the simvastatin-induced mitochondria impairment results from inhibition of the complex I of respiratory chain.

With respect to voting trees, while in general a learning algorithm would require an exponential number of samples, we show that if the number of leaves is polynomial in the size of the set of alternatives, then a polynomial training set suffices.

In all samples, we show that markers in the doublecortin- and calmodulin kinase like 1 (DCLK1) gene, are significantly associated with general cognition (IQ scores) and verbal memory function, resisting multiple testing.

Using data from independent datasets including over 900 primary tumour samples, we show that deregulation of the Let-7 pathway is specifically associated with the C5 molecular subtype of serous ovarian cancer.

Using additional normal-tumor paired samples we show that on rare occasions the aberrant methylation profile is due to loss-of-heterozygosity.

Applying our method to the genotyping of L1 insertions in human samples, we show that it is as accurate as "gold standard" site-specific PCR assays.

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Utilizing GBM samples, we showed that the mere knowledge of physical interactions of miRs and the expression change of the underlying interacting mRNAs allows a prediction of associated miRs that drive the expression of their targets.

In gastric cancer samples, we showed a positive relationship between PAK1 and RUFY3, and that increased expression of RUFY3 is positively correlated with clinical gastric cancer samples.

From analyses of 485 tissue samples, we showed that the novel epi-panel had a higher sensitivity and specificity than all the individual biomarkers.

Finally, although Tyrp1 protein (immunohistochemistry (IHC)) was only detected in about half of the samples, we showed that its expression also correlated with Breslow thickness.

In patient samples we showed that pneumolysin levels in CSF remained high after 48 hours in nonsurvivors of meningitis compared with survivors.

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