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The huge difference in miRNA expression between normal and tumor samples underlines the important role of miRNA deregulation in the development of breast cancer.
The high percentage of overlap between both databases for the human samples underlines the reliability, and the identification of a large number of novel PA sites in human and especially in chicken by MACE affirms the potential of this technique for the characterization of APA.
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The 8 markers investigated here behaved differently when assessed on T. b. gambiense or T. b. rhodesiense samples, underlining the differences between the two forms of disease, and suggesting that potentially new rhodesiense-specific markers could be discovered.
Fourth, this synergism not only occurs in established glioblastoma cell lines but also in primary glioblastoma cultures derived from tumor samples, underlining the clinical relevance of these results.
The number of regions across the entire genome that showed enrichment was very small and comparable between the 416B control and HA-T-VP64 PU.1-14 samples, underlining the high specificity afforded by TAL-mediated targeting reported by others (Mali et al., 2013).
Finally, the low influence of tissue composition on the sample clustering underlines the effect of the subtraction procedure in limiting the tissue heterogeneity effect.
Due to its design, the assay caters for degraded samples, underlined here by results from artificially degraded DNA and from simulated casework samples of degraded DNA.
Similar relationships were observed in the dog tumor samples, again underlining the close resemblance of the dog tumor samples to their human counterparts.
Hence, an obviously enhanced photocatalytic activity toward H2 evolution and selective oxidation of alcohols are obtained on optimized OMCNA samples, greatly underlining the advantage of molecular engineering in supporting nanostructured photocatalysts.
Taken together, the high number of antimicrobial active fungal samples in this study underlines the potential of this approach, combining treatment of fungi with small chemicals with a sensitive screening tool.
This underlines the fact that sampling statistics can be used to greatly improve confidence in both variant calling and RNA transcript counting applications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com