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We used a local BLASTx query [ 61] on a database of HIV-1 subtype B and C reference samples to translate the nucleotide fragments into their corresponding protein sequences (see Additional file 1).
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These hypotheses will require standardised clinical trials with proper patient tracking and sample handling to translate these molecular targets into meaningful clinical tools.
The y-axis of the coordinates was directed from the N pole to the S pole of the circuit, whereas the x-axis was parallel to the cylindrical axis of the vacuum chamber: The samples were expected to translate along the x-axis.
Appropriate clinical samples are needed to translate experimental findings into useful predictive biomarkers, and to confirm that therapeutic strategies stemming from basic research are relevant in patients.
Some agents are promising, but rigorous testing with appropriate study designs and sufficient sample sizes necessary to translate and implement these agents in daily practice are either absent or have generated disappointing results [104].
Next, we need to convert (3) from general sample format into discrete time format; to translate sample indices into discrete time values we use, where is sampling interval, which is an inverse of D/A converter's sampling rate.
Once the proxy models are constructed, a sampling method is needed to sample the factors and to translate the uncertainty from the input to the response.
Their answer was to translate samples into forms as easy to manipulate as they get: buttons, knobs, sequencers, and other professional mixing tools now take the forms of simple polygons.
A fine focusing stage (HRZ 200 stage, Carl Zeiss) is used to translate the samples after x-y scan of the samples for obtaining a large-area image, and to change the focus position for imaging at various depths.
It is thus still very difficult to extrapolate from these small samples to full populations, or to translate the scientific knowledge into clinically applicable information.
A separate piezo stage (NV40, Piezosystem Jena) was implemented to translate the sample with nanometer precision in the xy-plane.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com