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Specifically, both of them represent the unknown target distribution by a set of randomly drawn samples to avoid the intractable integrals.
We carried out the test separately on the CEU and YRI samples, to avoid the effects of this population structure on the analysis.
We discarded transcripts for which we did not detect expression in all samples or where expression was close to zero in all samples to avoid the effects of low read sampling error on expression levels (RPKM<1).
The other reason is that the definition can balance the positive samples and negative samples to avoid the training bias.
In this study, we used OF and DBS samples to avoid the difficulty of blood sampling from infants.
Mice were fasted overnight before administrating these samples to avoid the influence of food in the digestive tracts.
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Whole plant where sampled to avoid the random effects associated with bottleneck colonization of different leafs by different viral subpopulations.
We chose, however, to analyse the more stringent sample to avoid the influence of parity on the main outcome variables.
The catheter was inserted at least 30 minutes before the first blood sample to avoid the effects of insertion and was provided with an extension tube fixed to the neck of the goat with adhesive tape, so that it was possible to draw blood without restraining the animal.
We obtained maternal plasma from 10 mL maternal peripheral blood after centrifugation at 1,600 g for 10 min. Great care was taken in the collection of plasma samples to avoid taking the buffy coat or any blood clots.
It is therefore important to minimise the number of false positive IgM and IgG samples to avoid uncertainty for the physician and anxiety by the patient.
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