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Factors such as the limited availability of live patient samples, the failure of mouse models of fAD to recapitulate AD pathogenesis fully and the inability to study sAD in animal models suggest that live patient-specific cellular models would be especially beneficial to AD research, as long as they can accurately recapitulate important aspects of the pathogenesis.
It seems that despite clear evidence that altering biased attention for threat can reduce emotional vulnerability, and encouraging results with clinical samples, the failure of a number of studies to modify selective attention should be grounds for all researchers to cease investigations into the clinical applications of attentional bias modification using the internet.
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Overall raw intensity values increased in globin reduced samples despite the failure of GLOBINclear to completely eliminate the two most abundant globin transcripts, hemoglobin alpha (HBA2) and hemoglobin beta (HBB).
Figure 4 a shows a sample of the failure of co-registration if the software had followed the peak distribution in Fig. 3 b.
The low yield of microbiologic sampling and the failure of a wide spectrum, empirical anti-bacterial treatment are clues that should prompt clinicians to include invasive mycosis in the differential diagnosis of septic arthritis in immunocompromised patients.
A real-time PCR study of the same shrimp samples [10] determined that the IHHNV load was lowest in the Mazatlan samples, likely contributing to the failure of these samples to amplify.
For single slip oriented samples the failure behavior is a clear result of the localized deformation.
The proposed model not only accounts for the failure of samples under high cycle loadings, but also for the thermal effects during cycling in a unified theoretical framework.
The low efficiency of rRNA removal in these samples is probably caused by the failure of the subtractive hybridisation process used to eliminate rRNA in the RiboZero approach, which depends on the presence of intact 5′and 3′ends that are targeted by the capture oligonucleotide probes.
Here is a sample from Joel Klein's article The Failure of American Schools, which appeared in the 2011 Atlantic.
Second, small sample sizes often lead to the failure of detection of significant QTL (Beavis 1994, 1998).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com