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For fewer than 5 samples, the calculation did not reach stable results, but stable results were achieved for more than 5 patients.
In the evaluation of the estrogenicity of the environmental samples, the calculation of the e-EDC concentrations was the first goal achieved.
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In addition, blood samples for the calculation of capillary blood oxygenation were collected.
the weight given to the last sample in the calculation δ.
In the sample size calculation, the significance level was adjusted for the multiple primary outcome measures.
In order to decrease the influence of the variables unknown at the moment of sample calculation, the sample size was increased to 80 subjects.
According to the sample size calculation the number of patients should be 144 in each group, 288 in total.
According to the sample size calculation the study population was estimated to be 288 patients, 144 in each group.
The primary endpoint for the sample-size calculation was the maximum shear strength.
The results were used in the sample size calculation for the main study.
The sample size calculation for the three-arm RCT is based on the following parameters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com