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AA: amino acid, N: number of samples The advent of molecularly targeted therapy is shifting the paradigm of management of cancer patients from generalised chemotherapy and/or radiotherapy to personalised treatments with better efficacy and lower toxicity.
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Mid- and far-infrared spectroscopy of galaxies has become possible for sizeable samples with the advent of the Infrared Space Observatory ISO.
Dramatic advances in the understanding of these lesions may be expected with the development of more flexible microdissection systems (suitable for fresh/frozen samples) and the advent of high-throughput-technology methods suitable for the evaluation of paraffin-embedded tissues (e.g. CGH arrays).
The historical difficulties in identifying E. meningoseptica from other nonfermenting gram-negative organisms (including Pseudomonas species) in both patient and environmental samples mean that the advent of MALDI-TOF mass spectrometry might simply be helping to describe E. meningoseptica epidemiology, and the recent increase in reported outbreaks might indicate ascertainment bias.
Other investigators have applied additional requirements, such as eliminating genes that show changes in expression levels with collection or shipping of the samples [ 15], although the advent of RNA stabilization tubes for blood collection may make this less of a concern in future studies.
The advent of large samples of smart metering data allows policymakers to design Feed-in Tariffs which are more targeted and efficient.
But with the advent of computerised sampling technology, all and sundry were suddenly able to swipe his card into a soundtrack for their own aspirations.
This has been made possible with the advent of fully sampled matrix array transducer technology [ 22]. 3D-TTE has numerous proven uses in clinical practice.
Axillary clearance remains the standard surgical procedure for early breast cancer, despite the option of axillary node sampling (Steele et al, 1985) and the advent of sentinel node biopsy (McIntosh and Purushotham, 1998).
With the advent of Big Data era, sampling is gaining unprecedented popularity in various applications, since it is prohibitively expensive to compute an exact answer for each query, especially in an interactive system.
The advances in 3D echocardiography in particular the advent of a fully sampled matrix array transducer allowing real-time 3D-TOE has brought the echocardiologist to the forefront of catheter-lab-based procedures in structural heart disease.
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