Suggestions(1)
Exact(4)
DOI: http://dx.doi.org/10.7554/eLife.03772.020 The most likely explanation for the ligand-independent activity of IGF1R variants with single cysteine substitutions is that IGF1R samples the active conformation in the absence of ligand and becomes trapped in the active state by a disulfide bond.
In some samples, the active MMP-9 band was also present.
We believe these data provide persuasive evidence that (i) IGF1R TMs associate in the active state and (ii) unliganded IGF1R transiently samples the active state.
Note, however, that was well as the differences between bee pollen samples, the active compounds reported will also reflect variations in the actual bioactivities screened for and in the methodology utilized for screening for them as well as variations in the extraction and enrichment of the compounds.
Similar(56)
Then there is the margin of sampling error, which unavoidably occurs from randomly sampling the active residential telephone exchanges across the country.
= not significant For each tumor sample, the active and inactive forms of MMP2 and MMP-9 were measured by their gelatinolytic activities.
For the Stress Model mutational stress was not postulated to be the determinant factor a priori but, rather, it was derived from the assumptions of the model that are essentially two (1) there is a single active conformation and (2) mutants are flexible and therefore can sample the active conformation so that they are at least partly functional.
As reported elsewhere [ 23], a comparison of the genotyping samples from the active surveillance to an independent genotyping sample, taken on 168 sheep farms, shows a good correspondence.
The serum samples from the active SLE patients were acquired before the initiation or reinforcement of treatment, and the samples from the inactive SLE patients were acquired during regular hospital visits and then stored at -20°C.
In vitro analysis of the anti-HBV like activity was assessed by pre incubating the HBV positive serum samples with the active fraction by performing ELISA.
All four different assays presented expected E17βG signal profile in microgravity and on ground 1g conditions (Table 1), being MRP2+ samples the most active and MRPdef the less active group of samples in all gravitational conditions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com