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The exact oxidative lesions present in MOHCA-seq samples that result in RT stops are uncertain.
Clinical evaluation is generally performed by expert laboratories with defined patient samples that result in coefficients of variation and receiver operator analyses to determine performance characteristics.
This may result in effect-size estimates that are upward biased (referred to as "ascertainment bias"); this is caused by ascertaining only those samples that result in genetic loci with evidence of significant association.
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Samples that resulted in nondetects are reported together with the corresponding sample-specific limit of detection (SLOD), a useful tool when estimating the public health risk associated with the contact or ingestion of water.
Additionally, a value of 0.1 μg/L (the limit of detection divided by the square root of 2) was substituted for the four samples that resulted in concentration measures below the limit of detection.
This is associated with a reduction of the original content of AN in the composition of samples that results in reducing the amount of NH4Cl produced in reaction (2).
Only samples that resulted in CPE were processed for indirect sandwich ELISA.
Samples that resulted in 3 or 4 dots were considered seroreactive with IgM against R. typhi.
DNA samples that resulted in negative PCR for bacterial 16S rRNA were discarded.
Then in a subsequent step the actual SVR is computed for those samples that resulted in a large LVR.
Among 10 samples that resulted in the growth of NTM, 5 samples were negative and another 5 samples were contaminated by DLRPA.
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CEO of Professional Science Editing for Scientists @ prosciediting.com