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For the growth mechanism, an additional step can be introduced from the ring-shaped samples that explain the formation of holes and lobes.
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We also used principal-component analysis (PCA) to examine the similarity between samples according to the components that explain most of the variance in the data as shown in Additional file 1: Figure S1.
1) The authors should confirm that it is indeed sample homogeneity that explains the difference in affinities measured by ITC with apparently identical (or very similar) SNARE and complexin constructs.
However, it is not clear how to explain the lack of interactions as observed by the NMR experiments by Trimbuch et al. Major comments: 1) The authors should confirm that it is indeed sample homogeneity that explains the difference in affinities measured by ITC with apparently identical (or very similar) SNARE and complexin constructs.
Future studies, including the use of random samples, should examine the contextual factors that explain such differences in values and buy-in.
An unsupervised hierarchical clustering analysis was performed evidencing three main sample clusters (FBC1, FBC2 and FBC3) that explain a different behaviour of male patients with respect to female patients as regards miRNA expression.
Mesothelin protein was highly expressed in both mesothelial and stromal cells of the control samples, that could explain the non-differential expression of MSLN mRNA.
Over half the time, even lung samples grow out nothing that explains why a patient died.
In both cases, DELISHUS uses information of the entire sample to call genomic deletions that explains, in part, the increased number of deletion calls.
A principal component analysis of the smoothed correlation matrix at the genetic sample level yielded three principal components that explained a total of 88% of the variance.
Participants were to be interviewed about their experiences with the recruitment procedures, the breastfeeding guides and support, and the materials that explained breast milk sampling procedures.
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