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15 Its enrichment in PD-derived samples prompted us to investigate whether the abundance of exosomes is increased in PD using NTA in individually extracted patient samples.
The high degree of similarity between the patterns obtained in the CHB and JPT samples prompted us to combine the data from both populations and to treat the two populations as a single one named ASN (for Asian).
The results in human samples prompted us to perform similar analysis in the AD transgenic mouse model PS1xAPP.
The low sensitivity of NS1 antigen detection in our samples prompted us to perform NS1 gene sequence analysis.
The inverse correlation of Tbx3 and PTEN mRNA levels in HNSCC samples prompted us to analyze whether Tbx3 would cause a reduction in endogenous PTEN mRNA levels.
The significant increase of decorin expression in PE placenta samples prompted us to explore the possible biologic significance of decorin in the pathogenesis of PE.
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Also in the case of miR-93, its levels of expression are more heterogeneous in HGG samples, prompting us to verify a possible correlation of its expression levels with those of VEGF and IL-8.
The PCA results showed a molecular homogeneity shared by tumour samples, and prompted us to proceed in the subsequent statistical analysis without discriminating between epithelioid and biphasic subclasses.
Our observation of increased variance when calibrating with unadjusted sampling dates prompted us to re-estimate the age of the 1977 re-emergent lineage using a dataset free of sequences with biologically unrealistic sampling dates.
However, upon initial application of MiTCR to tumor RNA-seq data using the default parameters, we identified hundreds of non-specific and out-of-frame CDR3 sequences per sample, which prompted us to explore alternative parameters.
While the above data indicates that, on average, AS at the BRCA1 locus is similar in breast and blood samples, Δ5q findings prompted us to explore the possibility that more subtle splicing alterations targeting individual AS events in individual breast tumor samples do exist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com