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However, there are only small amount of positive CSF culture in the samples of neonatal bacterial meningitis [ 22].
In the case of TfRc2, a higher molecular mass PCR product, other than the expected classic isoforms α and β, was detected in all tissue samples of neonatal rats, while a single PCR product was detected in mRNA samples obtained from in vitro cultures.
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Histological cross-sections stained with picrosirius red to highlight the collagen were recorded under cross-polarized light on one sample of neonatal pericardium and one of adult pericardium [ 34].
Using a case-referent approach for the evaluation a three-year sample of neonatal deaths (450 cases) and randomly selected referents, 6% from the total population of live births (1120 referents), will allow to demonstrate an effect of the randomised intervention of 26% (OR 0.74, 95% CI 0.55-0.99).
We assessed clinician agreement with the Delphi panel by surveying a sample of 48 neonatal intensive care practitioners.
16 A purposive sample of four neonatal units was selected in each of three European regions: Ile-de-France in France, Lazio in Italy and the former Trent region in the UK.
Furthermore, similar and increased detection rates of S. agalactiae were found in screening samples of vaginal and neonatal colonization [ 23– 25], and increased detection was observed by real-time PCR for S. agalactiae in cerebrospinal fluid and blood from patients suspected of meningitis and sepsis [ 26].
With confirmation that the method was suitable for the analysis of neonatal samples, it was applied to samples homozygous and heterozygous for HbS.
Notably, these same patterns were also evident when we focused on only the expression of miRNAs identified previously as differentially expressed in naive cells: patterns in thymic samples were more similar to those of neonatal and newborn splenic samples than to the profile found in the adult spleen, which possesses the most distinct profile of all the samples.
We tested the application of bioinformatic algorithms in studying the metabolomic profiles of neonatal urine samples with clinical evidence of severe asphyxia at birth and subsequent neurodevelopmental handicap.
To do this we used a Taqman GPCR array to determine the global expression profile of non-chemosensory GPCRs in four independent samples of TG neurons from neonatal rats.
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