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In samples of benign prostatic hyperplasia (n=10), no FGF8b expression was detected.
Additional portions of thyroid tumours and samples of benign disease were frozen at −80°C for later Western blot analysis.
There was no significant difference in COX-2 positivity between samples of benign and borderline tumours (Table 1).
Samples of benign naevi and metastatic melanomas for RNA isolation were obtained from 2-mm diameter cores of FFPE blocks.
In addition, 39 samples of benign prostatic hyperplasia (BPH) patients (59 76 years of age; mean 68 years), who underwent transurethral resection of the prostate, were included.
Primary prostate epithelial cells were cultured from patient samples of benign prostatic hyperplasia and prostate cancer prior to treatment with PDT or gamma irradiation.
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All breast cancer cases and a selected sample of benign breast diseases were confirmed pathologically.
A section of tumour tissue and a sample of benign mucosa from the same organ were collected from each patient.
The IHC studies on paraffin-embedded samples of normal, benign, and malign ovary reveal that caveolins are present in normal ovarian surface epithelium, in benign pathology, and in early stages of tumor proliferation, with their expression being inhibited as the malignant transformation advances [ 111].
Seventeen (52%) of the samples of adjacent benign squamous epithelium showed SULF2 staining of this epithelium.
Seven (29%) of the samples of adjacent benign gastric epithelium showed SULF2 staining of this epithelium, mostly patchy in the basal layer with weak-to-moderate intensity.
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