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Unfortunately, initial cost of creating such models may be extremely high because of a large number of samples necessary to ensure reasonable accuracy.
Our approach intelligently determines the best allocation of simulation trials or samples necessary to maximize the probability of identifying the optimal ordinal solution.
Incrementing sample number from this point steadily reduces the likelihood of a biased survey; however, the number of samples necessary to drive the probability of survey availability events to a preferred level of infrequency may be daunting.
The bases of multivariate calibration are presented with special attention to some points usually not considered or underevaluated, i.e., the sampling design, the number of samples necessary to obtain a reliable regression model, the effect of noisy predictors, the significance of the parameters used to evaluate the performance ability of the regression model.
Moreover, the lower-dimensionality of X F, Y F compared to X I, Y I improves accuracy of the LR matrix estimation due to the Curse of Dimensionality[50], which states that the number of samples necessary to estimate a vectorial parameter grows exponentially with its dimensionality.
The MBRN database permitted a long observation period and the large samples necessary to study rare events.
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The temperature differences across the sample necessary to give the measured rates of advancement of the freezing front were calculated to be 18.8 °C, 13.9 °C and 9.1 °C for volume fractions of dispersed phase of 0.032, 0.064 and 0.128, respectively.
36 In the second phase, we used a larger sample, necessary to verify the results obtained in this pilot study.
The IC50 value is defined as the concentration of sample necessary to inhibit 50% of the cells.
Such a trial is unlikely to take place, however, because of questionable ethics and because the sample necessary to detect a significant difference would be prohibitively large.
Another challenge is that the amount of sample necessary to perform these analyses is often significant and can be difficult to obtain in pediatric or severely ill patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com