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While new high throughput methodologies allow for the XCI status of more genes to be examined in an increasing number of tissues, studies examining non-clonal samples must take into account the level of skewing of XCI within each sample, which has not been done in all cases [ 31].
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To appropriately quantify environmental concentrations of chloramines, air or water sampling must take place within hours of identification of a possible outbreak and before changes have been made to pool chemistry or ventilation.
In both these definitions, the final sample must have been taken at least 28 days after the previous sample.
Clinical or post-mortem suspicion of salmonella infection is notifiable for all veterinarians, who must take relevant samples in case of such suspicions.
Veterinarians must take abortion samples if more than one abortion has happened within 4 months on the same farm, and the samples are tested for, among other pathogens, Bm [ 10].
Other times the doctor must take a sample of tissue and send it to a lab for evaluation.
Instead, a laboratory technician must take a sample of sputum coughed up from the lungs, stain it and inspect it under a microscope for the telltale bacteria, which resemble long-grain rice.
This however relies strongly on both the length of the follow-up time and the size of the sample, as all the transitions must take place a minimum number of times to give reliable predictions.
Because lead enters drinking water so late in the pipeline, samples must be taken from the taps of individual structures rather than from a central distribution point.
The analysis and sample size estimation for such designs must take the clustering into account or the resultant significance tests (P values) and confidence intervals will be in error [ 1].
Consequently, the specific properties of samples must be taken into consideration when designing pressure supported processes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com