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Sequencing the nucleic acid content of individual cells or specific biological samples is becoming increasingly common.
Given this development, the availability of thoroughly phenotyped patient and control samples is becoming even more important.
Molecular evaluation of microeukaryotic communities in environmental samples is becoming an increasingly studied subject, indicating that the diversity of this group is higher than previously described [5], [50], Indeed, very little is known about such diversity in many ecosystems.
The ability of polymerase chain reaction to produce consistent, artefactual allelic loss, especially in archival samples, is becoming increasingly well documented.
With the wealth of data produced by current genomic technologies, collection of multiple types of genomic data on a set of samples is becoming commonplace.
Thus, a test of the bifactor model not involving clinical samples is becoming a very recent trend in HADS research, although published studies are still rare for community samples [ 26].
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Bone biopsy samples are becoming widely used to monitor the effects on trabecular architecture and mineralization in clinical studies during the treatment of bone diseases.
Free samples are becoming as standard a part of all electronic booksellers' operations as readers' reviews and ratings.
However, internet usage is increasing and thus "online samples" are becoming more like a general population sample in the US.
(In fact, the demands for coded samples are becoming the rule compared to the use of anonymous samples just a few years ago).
Existing methods for estimating richness and community structure from observed samples are becoming more refined, improving model estimation, confidence quantification and comparative methods [ 7 9].
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