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Following recent controversy about unanticipated genetic research being conducted with Havasupai samples in the US, further empirical research to determine attitudes to ongoing uses of samples and data from specific communities is desirable [ 43].
Low levels of BPA can be detected in over 90% of human urine samples in the US, indicating that exposure to BPA is widespread.
As one of the first studies to examine these relationships in a US sample, these findings should be replicated in other, more diverse samples in the US and other developed nations.
The lifetime prevalence of BED has been assessed in large population samples in the US [ 45, 47] and Europe [ 46].
Simon et al. [ 5] investigated 9125 representative samples in the US, and found that obesity was associated with significant increases in lifetime diagnoses of major depression, bipolar disorder, and panic disorder or agoraphobia.
Overall, binge drinking is relatively prevalent; data from representative samples in the US suggest a 30-day period prevalence of 17.1% [ 9], while data from Brazil suggest that 26.7% had at least 1 episode of binge-drinking in the past year [ 10].
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In addition, one-on-one in-depth interviews were conducted with males with PE and female partners of men with PE in the UK, Italy, France, Germany, and Poland (interviews also were conducted with a sample of men in the US).
This involved analysing the expression of all 667 miRNAs across all 48 samples in the discovery cohort allowing us to choose one of the least variant miRNAs.
The sample period includes three major changes in the US immigration law: The Immigration Reform and Control Act (IRCA) in 1986, the Immigration Act (IA) of 1990, and the Illegal Immigration and Responsibility Act (IIRA) of 1996.
Moreover, genetic variance in physical health has shown a similar association with education in this Danish sample [21] and to income in the US-based sample [31].
Other samples in the Registry include bowels and penises.
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