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This study, while primarily designed as a method validation, has demonstrated that BPA can be detected in human fetal liver samples as early as the third month of fetal life.
The insights gained from these breakthrough studies led Pace to propose the idea of cloning DNA directly from environmental samples as early as 1985.
In cells treated with R-FSL1, there was a rapid up-regulation of TNFα mRNA transcripts, as demonstrated by RT-PCR, with cDNA synthesis apparent from these samples as early as 15 minutes following stimulation.
Secondly, these differentially expressed miRNAs can be detected in both tissue samples and saliva samples as early as at LGD stage.
Our data suggest that these gene markers can be identified in CRC samples, as early as stage II, but are not solely stage II specific.
In the current study, HSPs appeared to be substantially accumulated in cells immediately after heat stress exposure, since HSP70, HSP80 and HSP90 expression levels were found to be significantly induced, compared with control samples, as early as after 1 h of exposure to 42°C.
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The Cariostat test has reliably predicted caries experience in the short term in toddlers, and in the long term by sampling as early as age 3 and predicting df outcomes as long-term as age 10.
The first case of a fatal form of the disease was documented in 1995, though tissue samples from as early as the 1980s have since tested positive for the virus, and localized skin lesions in wild African elephants were recorded in the 1970s.
We found signs of chytrid in archived samples from as early as 1998.
The observed variability within the sequences of the two groups, together with its detection in samples collected as early as 1994 from Egypt and Morocco (Table 1), indicates that the virus has not emerged only very recently.
Since our cohort of ALL patients included samples diagnosed as early as 1996, the fact that the canonical aberrations were not detected at diagnosis could be due to technical limitations of the methods applied at that time.
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CEO of Professional Science Editing for Scientists @ prosciediting.com