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These sequencing-based methodologies present additional challenges as FFPE-derived samples are acknowledged to give rise to sequencing artefacts, complicating data analysis [ 12, 29].
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The assistance of Dr. A. Hajnal, Serologic Laboratory of the National Blood Transfusion Service, Budapest, Hungary in providing control blood samples is acknowledged.
The limitations of using the modified COSMIN scoring for small sample sizes are acknowledged.
Secondary outcomes will be scored according to standard methodology, but the limitations of the small sample size are acknowledged.
Although this study makes use of a very large population sample, some potential limitations are acknowledged.
Hiroshi Okada (Botanical Gardens, Osaka City University), the temple Mito Hachimanguu and Yoshiko Mashiko (Ibaraki-ken, Japan), Wolfgang Schwarz (Technische Universität München) and Josef Bogner (Ludwig-Maximilians-Universität München) are acknowledged for providing samples of O-ha-tsuki plant material or for their help to do so.
At AkzoNobel Brenda Rossenaar and Wilma Ravesloot are acknowledged for STEM-EDX sample preparation and analysis.
The nature management authorities at Svalbard are acknowledged for allowing us sample plant material.
M. Versteeg and D. C. R. Hermus are acknowledged for their help with collecting samples.
Nol Jansen and Herman Raaijmakers are acknowledged for their assistance in taking samples on Dutch pig herds.
Several limitations are acknowledged.
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