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Histology and tumor response, as eligibility criteria, are readily available, without the need for collecting and analyzing blood or tumor samples, and validating the biomarkers prospectively, a process which can be expensive, time-consuming, and delay treatment.
The RF repeats the procedure that consists of the following two steps: constructing the decision tree by using the randomly selected samples and validating the tree using the out-of-bag samples.
We investigated means of improved reporting of cfDNA yield by comparing quantitative PCR measurements of seven different reference gene assays in plasma samples and validating these with digital PCR.
In all cell lines, the amount of spiked zinc measured was within 10% of the expected value, suggesting that the activity of HcZ9 is not significantly altered by various biomolecules in these biological samples and validating the ability of HcZ9 to quantify mobile zinc in cell lysates (Supplemental Figure S11).
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Measurements were made with spiked samples and validated with polluted field-collected samples.
This optode was applied to determine Gd III) in synthetic and water samples, and validated with certified reference materials (CRMs).
The proposed method then was successfully applied to measure CAP in contaminated milk samples and validated by a commercially available enzyme-linked immunosorbent assay (ELISA) method.
Hepsin was found to be overexpressed in most tumor samples, and validated by immunohistochemical analysis [ 14].
We identified two different datasets from these Affymetrix chips containing breast cancer samples and validated the profiles in different subgroups of samples from these two datasets.
designed and performed experiments, K.K., K.I., H.S., and S.K., collected clinical samples and validated data, T.H. performed pathological study, and S.E. and K.T.-K.
The selected genes belonged to the PAM discriminatory genes between CRC and normal, and between adenoma and normal samples, and validated Taqman assays were available.
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