Exact(3)
Moreover, using mortality as an outcome measure requires larger samples and risk adjustment for fair comparison among providers and organizations [38].
In conclusion, we observed no associations between telomere length in these samples and risk of low- or high-grade dysplasia, so our study provides little support for this approach.
A recent study [ 26], carried out in Finland, examined 110 cases of soft tissue sarcoma and 227 hospital controls; exposure to dioxin was measured using the concentrations found in sub-cutaneous fat samples and risk did not increase with exposure; rather, the lowest level showed the highest risk in all types of analysis.
Similar(5)
However, the drop in performance varied depending on the sample and risk adjustment method.
Regression coefficients were estimated for the multivariable model including all variables using the training sample, and risk scores were predicted for the remaining tenth subsample (the test sample).
Cumulative survival time of high-risk samples and low-risk samples was calculated by the Kaplan-Meier method [17] and analyzed by the log-rank test [18].
Globally, similar results were obtained when comparing LNM positive N1 (n = 206) vs LNM negative N0 (n = 214) PTC samples and high risk (n = 24) vs low risk (n = 171) PTC samples (Additional file 1: figure S2).
When studies from both population based samples and high risk populations were pooled, white matter hyperintensities were associated with an increased risk of death during follow-up (2.0, 1.6 to 2.7, P<0.001; fig 4, also see web extra fig 5).
Related(2)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com