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Libraries 4 6 used 96 ApeKI Y-shaped adapters with internal barcodes (ICGMC 2015), and library 7 used these 96 Y-shaped adapters and 4 different PCR primers with different index barcodes (384 total samples) (adapted from Peterson et al. 2012) (Table S1, Figure S1).

Each participant was provided with a saliva sample collection kit (Sarstedt Corp., Montreal, Canada) with stepwise instruction for collecting saliva samples adapted from sample collection procedures described in the literature (King et al. 2000).

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Fig. 1 a RF APGD plasma jet generator as the core component of the ARTP system treating a microbial sample (adapted from Zhang et al. 2014).

The protocols for obtaining synthetic arsenate-doped 2-line ferrihydrite by adsorption (initial AD samples) or co precipitation (initial CP samples) were adapted from standard methods [16, 17].

Analyses of natural samples were adapted from: [19] [22] [109-115].

The GC-MS analytical method for hydrocarbon and fatty acid samples was adapted from Guan et al.[ 65].

n: Total number Chi-square: Value of the chi-square test DF: Degrees of freedom Control samples are adapted from literature.

In the absence of suitable sampling frames for migrant parent households, CHAMPSEA employed a three-stage flexible quota sampling strategy adapted from "sentinel site surveillance" methods (Byass et al., 2002; Wilson, Huttly, & Fenn, 2006).

Prior to World War II, strip sample methods adapted from European designs, such as that used in Finland's general survey (Ilvessalo 1927), were common across the country.

Households were randomly selected using a two-stage sampling approach adapted from the methodology of the World Health Organization Expanded Programme on Immunization (EPI) Cluster Survey Design [ 35].

At the end of each four-month survey interval, NHS trust record-keeping departments were asked to collate the sample of patients using sampling instructions adapted from those used for the national Inpatient Survey to allow the addition of ward information.

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