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The algorithm performed well in a separate validation sample with good discrimination and calibration.
Here, we use a sample with good power and sequencing resolution to provide insight into genomic characteristics of 5hmC in the brain.
While the algorithm itself does not make a diagnosis of ovarian cancer, it performed well to identify high risk women in a separate validation sample with good discrimination and calibration.
We had a sufficiently large sample, with good adherence rates and data coverage, to provide robust estimates of effect sizes and also a relatively "real-world" sample, for example, with many previous depressive episodes and concurrent comorbidities.
Strengths of our study include the use of a large population-based sample with good quality and completeness of information on stage at diagnosis, and the use of a flexible parametric model, allowing for the smooth estimation of excess mortality throughout the follow-up period while appropriately accounting for the effects of deprivation and age (Rutherford et al, 2013a).
We analyzed the effects of FTO rs9939609 on BMI in a large sample with good representation of the general population of northern Finland using SEM, taking advantage of data on a large selection of nongenetic exposures associated with BMI during the life course.
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Furthermore, doping hexaaluminate by Pt led to samples with good activities and high stability.
This procedure allows the determination of palladium in synthetic and real samples with good reliability of the determination.
Furthermore, the sensor L has been used to quantify Fe3 + ions in practical water samples with good recovery.
Moreover this sensor has also been successfully applied to detection of Hg2+ in natural water samples with good recovery.
Furthermore, the fluorescent reagent was employed to measure the Zn2+ concentrations in real water samples with good accuracy.
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