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A sample which excluded patients with significant co-morbidity would have enabled a more straight-forward comparison between age-matched peers and TKA recipients, and eliminate the variability in walk tests due to factors other than the TKA surgery.
In the sensitivity analysis carried out on a smaller sample which excluded those admissions used for development of the ICNARC physiology score, all three models performed somewhat less well.
Where the authors used a denominator that did not include all the participants originally randomised (eg, a sample that the author described as the 'analysis sample,' which excluded drop-outs and thus had smaller numbers at follow-up) we recomputed the data based on the same percentage loss to never-smokers using the numbers originally randomised.
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Note that these results apply to the sample which excludes coresident children.
To determine mitochondrial density and area, twenty-two fromds from BF and twenty-two fromdSFfrom samplesles, which excluded nuclear areas, were randomly selected.
We observed more growth retardation in the Fukushima May samples than in the Shiroishi May samples, which excluded the possibility of an edge effect, as discussed in Point 2. For the eclosion and pupation data in both the May and September/October samples, the most affected population was from Hirono, approximately 20 km from the NPP.
There was a systematic bias against severe disability due to the sampling method which excluded people who were too disabled to complete the survey.
Additional concerns about this analysis included its complex sample selection scheme, which excluded a large number of NA-ACCORD patients.
All patients underwent OPB sampling before panendoscopy with oesophagoscopy, which excluded a second oesophageal tumour.
The former had an overall RMSE value of 0.067 cm cm−3, and the latter a value of 0.072 cm cm−3 when tested on the TEST_BASIC set, which excluded the samples originating from HYPRES.
Average deviations between the split frequencies were <0.01 in all analyses and a 'burn in' which excluded half the sampled trees was used to generate a consensus tree.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com