The protein is thought to have appeared after a spontaneous genetic mutation and was found after a tissue sample was submitted for testing by the World Animal Health Organization (OIE).
2500 ng of each sample was submitted for genotyping to GeneSeek, Inc. (http://www.neogeneurope.com).
For BUN and creatinine, two samples were submitted for control and 40-mg/kg dose and one sample was submitted for the 60-mg/kg dose (each submitted sample contained serum from five different mice).
For grossly positive lymph nodes, it is recommended that a representative sample be submitted for microscopic confirmation.
Our study was restricted to the subgroup of aortitis patients with complications requiring a surgical procedure, and for whom a surgical sample was submitted for pathologic examination.
The proportion of patients for whom a tissue sample was submitted for pathologic examination differed greatly by surgical center in Denmark, ranging from 35%to69%9%.
Pathologic examination occurred less frequently in patients with a diagnosis of endocarditis, perhaps because a tissue sample was submitted for bacterial culturing rather than for pathologic examination.
Approximately 50 μg of each isolated PLA2 corresponding to approximately 2 nmols/mL sample was submitted for N-terminal amino acid sequencing using the automated Edman degradation method [ 13] on a PPSQ-33A (Shimadzu) automatic sequencer.
Three fully viable metastatic nodules (measuring 2 mm, 6 mm, and 11 mm) were resected after 7 cycles (6 months) of cyclophosphamide plus topotecan relapse therapy, at which time a sample was submitted for drug-sensitivity testing to evaluate the activity of 5 different regimens with 1 investigational drug arm.
To characterize the intestinal microbial composition before immune-mediated colitis, faecal samples were submitted for bacterial microbiota profiling using 16S ribosomal RNA sequencing on the Illumina MiSeq platform.
