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Three variables (resin amount, sample volume, flow rate) were regarded as factors in the optimization.
FIA parameters (sample volume, flow rate, distance between injection valve and sensor) have been optimised in terms of high throughput, minimum dispersion, fluid consumption, sensitivity and reproducibility.
Several parameters like effect of pH, sample volume, flow rate, type of eluent, and influence of various ionic interferences, etc. were evaluated for effective adsorption of palladium at trace levels.
Several parameters concerning adsorption behavior, including sample pH, sample volume, flow rate, type of eluent, and effect of ionic interference, etc. were evaluated for effective and selective adsorption of molybdenum.
Generally, in SIA that involves a developing reaction, it is recommended to utilize a chemometric tool for optimizing effective conditions (i.e. sample volume, flow rate and major reagent concentration) while less effective conditions could be fixed at suitable levels. .
Generally, in SIA that involves a developing reaction, it is recommended to utilize a chemometric tool for optimizing effective conditions (i.e. sample volume, flow rate and major reagent concentration) while less effective conditions could be fixed at suitable levels.
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Flow rate of KIO3 solution, sample volume, carrier flow rate, and reaction coil were the selected factors for evaluation.
For the optimization phase, a centered face composite design 22 + star was employed to evaluate sample volume and flow rate of KIO3 solution, which were the factors identified in the screening phase as having more influence on the absorbance signal.
In vis-spectrophotometric SIA methods those involve developing reactions with two reagents (major and minor), conditions affecting method performance are in the following order: sample volume > flow rate ≈ major reagent concentration >> major reagent volume ≈ minor reagent concentration >> minor reagent volume.
An empirical mathematical model was designed which establishes the relationship between the variation of the responses (extraction yields), and the variation of three factors (sample volume, sample percolation flow rate and amount of metallic ions present in the sample).
Fig. 1 Effects of pH on the recovery of Cd, Cu, and Pb, 0.2 μg/mL; solid phase, 200 mg; sample volume 500 mL; flow rate 3 mL/min; elution solution 10 mL of 1 M HCI).
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