The selectivity of the analytical procedure is sufficient to analyze samples of very complex matrices (e.g., wastewater).
This complicated proteomic analysis because the remaining samples were very complex, biasing all identifications toward high abundance proteins.
Karyotypic information for anaplastic thyroid carcinomas is more difficult to interpret, as it is limited to 8 samples displaying very complex and incompletely described karyotypes.
Since the protein samples are very complex and the high and medium abundant proteins did not seem to be affected by the treatment, a reduction of the complexity could be considered.
Primary tumour samples had very complex karyotypes with many structural aberrations, whereas the two cell lines, especially COR-L23, were less complex and harboured only a few translocations (two in COR-L23 and 15 in COR-L105, compared with a mean of 32 in the primary tumour samples).
Murine xenotransplantation studies using primary patient samples can be very complex and relatively expensive.
Another shortcoming is that the observed effects showed sometimes very high variability within tested samples, indicating the very complex nature of these Abs.
The conductive transfer of thermal energy, which is a major mechanism responsible for the generation of PA signal in the powdered samples, is a very complex process.
To investigate the application of the slip flow capillary to a very complex sample, the water-soluble fraction of an E. coli protein mixture was studied.
The single-step procedures were found to be ineffective even with highly selective detection parameters due to very complex sample matrices.
