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A hold out sample validation exercise further emphasizes the improved accuracy of the models with spatial and temporal interactions.
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Table 4 resents results of the out-of-sample validation exercise.
Two separate stock solutions of LS were prepared for bulk spiking of calibration standards (CS) and quality control (QC) samples for method validation exercises as well as incurred sample analysis.
Samples from animals exhibiting even subtle signs of BSE are most likely to behave as field samples used in validation exercises used for test approval.This study elucidates the relative performance of these tests solely on experimentally generated C-Type BSE, serially diluted in known BSE-negative tissue homogenate, and not necessarily on C-type BSE occurring by natural means.
In addition, a small validation exercise was undertaken by cross-referencing a sample of randomly selected cases with the UK National Health Service National Strategic Tracing Service NSTSS) records.
Limitations include unpredictable sample representation, development of compromise position rather than consensus, and absence of blinding in validation exercise.
We conducted a data validation exercise in four randomly selected district hospitals (10% of the total sample) to check the accuracy and determine the reliability of the data.
Standard solutions and spiked samples of the main toxin, okadaic acid, were used at the beginning of the validation exercise to avoid cross-inhibition of other toxins that would otherwise deteriorate the quantitative significance of the data.
Since the validation exercise makes specific productivity assumptions, it also allows for direct estimates of annual sample processing capacities for each type of laboratory.
As our reported error rates are based on a sampling of facts from the respective databases, we expect fluctuation in the reported error rates each time the validation exercise is repeated.
Is the validation exercise feasible?
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