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"Robots enable one to set up much smaller crystallization drops, so that you need smaller amounts of sample to screen large numbers of conditions," says Cynthia Wolberger, a professor of biophysical chemistry at Johns Hopkins School of Medicine in Baltimore, Maryland.
Cervical mucous is potentially an ideal sample to screen for biomarkers for early detection of cervical cancer.
The expression levels of 30 common human pro-/anti-inflammatory cytokines were detected simultaneously within each sample to screen for any candidates whose levels were significantly altered.
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Physicians had long obtained chest X-rays and sputum samples to screen for lung cancer in healthy patients, but studies in the 1960s showed that these tests did not lower mortality from lung cancer; researchers are now studying whether CT scans may be a better screening option.
Researchers at Purdue University have developed a tool for rapid salmonella detection called a continuous cell concentration device, which could make it possible to routinely analyze food or water samples to screen for pathogens within a single work shift at food processing plants.
Future studies will include larger patient populations and prospective CSF sampling to screen for incipient AD.
The other approach is to use genotyping in pooled samples to screen for the putative rare sequences in a very large number of individuals [21].
We demonstrate along with other recent publications [20] [22] that it is possible to use pooled samples to screen for rare SNPs in large pools and after quality control obtain reliable allele frequency data.
Consenting participants provided urine samples to screen for recent heroin, cocaine, marijuana, and amphetamine use.
The dental professionals performed the oral screening for OPMD, and they collected oral brush samples to screen for HPV infection.
This screener has been used with treatment-seeking populations and community samples to screen for drug use severity and dependence [ 13].
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