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While, the preferred method would be to derive health state valuations from a population sample, the mapping algorithm facilitates cost-effectiveness and burden of disease studies through proxy health state values that can be derived from the numerous oral health studies that have collected data using the OHIP instrument.
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(XLSX 9 kb) Additional file 8: The indices sequences and the codes for each sample of the mapping population.
In both samples, the mapping-model overestimated the EQ-5D utility scores for patients with low observed EQ-5D utility scores.
For example, a large ore body may extend for great distances underground in three dimensions, but mineralogical clues can direct sampling for the mapping effort.
Samples for the mapping populations were chosen randomly from germinated seed within each population.
A panel of 170 of 317 informative SSR markers was used to genotype the DNA samples of the mapping population.
In this genotyping assay, 95 DNA samples of the mapping progenies were genotyped (73 for C14xC15 and 22 for C15xC14).
Their Bland-Altman plot shows that, for the 12 patients (4.5 %) with the lowest health utility value in the sample, the mapping-derived index score (mean = −0.118, range = −0.370 to 0.118) was apparently smaller than the valuation-derived index score (mean = 0.261, range = −0.111 to 0.487) (Fig. 1).
With the outliers removed from the sample, the PC map based on the top two PCs does give the ring shape of the population structure.
In the developmental sample, the Velicer MAP criterion achieved the minimum value for the solution comprising two factors.
We used 50% of the sample to generate the mapping function (i.e., estimation sample) and, the other 50% to validate the model performance (i.e., validation sample).
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