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Like the Moroccan index, the IQBP is a downgrading type index; that is to say, for a given sample, the index value corresponds to the lowest sub-index associated with the most problematic substance.
Using a single row per sample, the index on each CASTOR table is 55 Kb (7000 samples × 8 character sample id) allowing for very rapid load times.
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In tumor samples the index was significantly higher; no significant differences were found between cancer types.
Laboratory personnel were blinded regarding the case-control status of each sample, and the samples of the index and matched control mother were analyzed coded in the same test run.
The details of the samples with the sample index are provided in Supplementary Table 1, and here we focused on the mainly contributed samples.
Associations of alleles among different loci were examined in each sample using the index of association (IA) statistic, which is a generalized measure of multilocus linkage disequilibrium [59].
Confirmation in an independent biological sample from the index case or an affected relative.
Furthermore, the change of the SAA in the research sample is the index test for the diagnosis of neonatal sepsis.
To reduce the sensitivity of chi-square to sample size, the index is divided by the degrees of freedom.
For patients with multiple contacts with a GP cooperative within the study period, only the first contact was included in the sample as the index contact.
All mutations were reconfirmed on a second blood sample from the index case before offering counselling and access to genetic testing for at-risk adult family members.
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